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Product Name | SGC-iMLLT |
Description | An inhibitor of the YEATS domain-containing proteins MLLT1 and MLLT3; binds to the MLLT1 YEATS1 and MLLT3 YEATS3 domains (Kds = 129 and 77 nM, respectively); selective for YEATS1 and -3 over YEATS2 and -4 (IC50s = >10 µM), as well as a panel of 48 bromodomains at 50 µM; inhibits histone H3.3 interactions with MLLT3 (IC50 = 400 nM in a reporter assay); decreases expression of MYC and DDN in MV-4-11 leukemia cells at 1 µM |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MLLT-1 3 MLLT1YEATS MLLT3YEATS H-3.3 MV411 MV4-11 4 bromo domains |
Gene, Accession, CAS # | CAS: 2255338-25-9 |
Catalog # | 28113-5 |
Price | $90.00 |
Order / More Info | SGC-iMLLT from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |