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Product Name | CUDC-101 |
Description | A multi-target inhibitor that potently blocks EGFR and HER2 (IC50s = 2.4 and 16.4 nM, respectively) and inhibits the activity of class I and class II HDACs at nanomolar concentrations (e.g., IC50s = 4.5, 12.6, 13.2, and 11.4 nM for HDAC1, 2, 4, and 5, respectively) |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | inhibitors histones deacetylases cancers receptors biochemistry proteins kinases apoptosis epigenetics signals transductions intracellular signaling biochemicals 1012060-66-0 CUDC 101 CUDC101 multitargets multi-targets targets multi combines functional groups potent humans epidermal growths factors HERs HDACs blocks tyrosines EGFRs HER1s HER2 HER-1 HERs ones twos HER-2 2s 1s inhibits classes I II activities activity prevents preventions cells in vitro slows tumors induces inducing regressions xenografts models acquired resistances single-targets singletargets singles blocks blocked blocking proliferations proliferating proliferates reduces migrations |
Gene, Accession, CAS # | CAS: 1012054-59-9 |
Catalog # | 16426-25 |
Price | $324.00 |
Order / More Info | CUDC-101 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |