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Product Name | SEL120-34A |
Description | A dual inhibitor of Cdk8 and Cdk19 (IC50s = 4.4 and 10.4 nM, respectively); selective for Cdk8 and Cdk19 over a panel of CDK/cyclin complexes at 1 µM; inhibits IFN-γ-induced phosphorylation of STAT1 in HCT116 colon cancer cells at 0.1-5 µM; inhibits proliferation of MOLM-16, MV4-11, and KG-1 cells (GI50s = <1 µM); reduces tumor growth in a KG-1 mouse xenograft model at 60 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1609522-33-9 SEL12034A SEL-12034A 34-A Cdk-8 19 IFNγ STAT-1 HCT-116 MOLM16 MV411 KG1 |
Gene, Accession, CAS # | CAS: 1609452-30-3 |
Catalog # | 27906-1 |
Price | $61.00 |
Order / More Info | SEL120-34A from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |