5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine from CAYMAN CHEMICAL COMPANY
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| Product Name | 5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine |
| Description | An mPGES-1 inhibitor (IC50s = 66 and 2,730 nM for human and mouse enzymes, respectively); selective for mPGES-1 over COX-1 but does inhibit COX-2 at 20 µM; inhibits LPS-induced PGE2 production in mouse peritoneal cells (IC50 = 12 nM); reduces carrageenan-induced paw edema in rats at 25 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | mPGES1 COX1 COX2 PGE 2 |
| Gene, Accession, CAS # | CAS: 2253745-78-5 |
| Catalog # | 31338-1 |
| Price | $130.00 |
| Order / More Info | 5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY