Col003 from CAYMAN CHEMICAL COMPANY

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Product NameCol003
DescriptionAn inhibitor of the collagen-Hsp47 protein-protein interaction (IC50 = 1.8 µM); decreases procollagen secretion from, and reduces the collagen levels in the ECM of, primary MEFs at 100 µM; a PBP2 inhibitor (IC50 = 128 µM); decreases the growth of wild-type, penicillin-resistant, and penicillin- and cephalosporin-resistant N. gonorrhea strains (MIC50 = 4, 8, 16 µg/ml, respectively); reduces collagen-induced, but not arachidonic acid- or thrombin-induced, isolated rat platelet aggregation at 50 µM; increases the time to occlusion induced by ferric chloride in carotid arteries in rats at 50 µM; reduces brain infarct area and cell death, as well as improves grip strength, in a rat model of MCAO-induced ischemia-reperfusion injury at 50 µM
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesCol 003 Hsp 47 pro-collagen extra-cellular PBP wildtype Neisseria
Gene, Accession, CAS #CAS: 328565-16-8
Catalog #39528-10
Price$175.00
Order / More InfoCol003 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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