GSK126 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for GSK126 products.
| Edit | |
|---|---|
| Product Name | GSK126 |
| Description | A selective, SAM-competitive small molecule inhibitor of EZH2 methyltransferase activity (Ki = 0.57 nM; IC50 = 9.9 nM versus that of EZH1: Ki = 89 nM; IC50 = 680 nM); inhibits global H3K27me3 levels, inhibiting the proliferation of EZH2 mutant DLBCL cell lines (IC50 = 28-61 nM) as well as the growth of EZH2 mutant DLBCL xenografts in mice receiving a daily dose of 50 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | histone H3-lysine H3 H3K27 methyltransferase EZH2 inhibitor inhibit HMT cancer GSK-126 S-adenosyl-methionine SAM S-adenosyl methionine S-adenosylmethionine trimethylation trimethylate PRC2 PRC-2 gene DLBCL xenografts chromatin research epigenetic modification KMT6 |
| Gene, Accession, CAS # | CAS: 1346574-57-9 |
| Catalog # | 15415-5 |
| Price | $120.00 |
| Order / More Info | GSK126 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY