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Product Name | RJR 2429 (hydrochloride) |
Description | An agonist of nicotinic AChRs; selective for α4β2 or α7 subunit-containing nicotinic AChRs (Kis = 0.7 and 10.9 nM in isolated rat cortex and isolated rat hippocampus, respectively) over α1βγδ subunit-containing nicotinic AChRs (EC50 = 1,000 nM in PC12 cells); induces dopamine release from isolated rat striatal synaptosomes (EC50 = 2.4 nM) and increases nicotine-induced elevations in epinephrine and norepinephrine levels in isolated rat adrenal gland at 100 µM; inhibits nicotine-induced ion flux in isolated rat thalamic synaptosomes (IC50 = 154 nM) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 91556-75-1 RJR2429 α-4-β-2 α-7 α-1-βγδ PC-12 |
Gene, Accession, CAS # | CAS: 1021418-53-0 |
Catalog # | 29745-10 |
Price | $184 |
Order / More Info | RJR 2429 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |