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Product Name | GDC-0623 |
Description | A potent, ATP-uncompetitive inhibitor of MEK1 (Ki = 0.13 nM in the presence of ATP); inhibits the proliferation of A375 BRAF(V600E) and HCT116 KRAS(G13D)-mutant cancer cell lines (EC50 = 7 and 42 nM, respectively); upregulates pro-apoptotic BIM |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1443238-25-2 MEK1 MEK-1 MAP GDC0623 ATP-uncompetitive A375 BRAF V600E HCT116 KRAS G13D ERK BIM phosphorylation GW620 |
Gene, Accession, CAS # | CAS: 1168091-68-6 |
Catalog # | 19479-25 |
Price | $302.00 |
Order / More Info | GDC-0623 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |