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Product Name | SD-1029 |
Description | A JAK2 inhibitor; inhibits autophosphorylation of recombinant JAK2 at 30 and 100 µM; decreases levels of phosphorylated JAK2, but not JAK1 or Src, in MDA-MB-468 and OVCAR8TR cells at 10 µM; decreases levels of phosphorylated STAT3 in MDA-MB-468, MDA-BM-435, OVCAR8TR, and SKOV3TR cells and inhibits IL-6-induced nuclear translocation of STAT3 in BHK-21 and U2OS cells at 10 µM; decreases the viability of and increases levels of cleaved caspase-3 in SNU-387, SNU-398, HepG2, and Huh7 hepatocellular carcinoma cells at 10 µM; inhibits hepatitis A virus replication in GL37 cells at 100 and 1,000 nM |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | JAK2 Inhibitor III|Janus-Associated Kinase 2 Inhibitor III |
Gene, Accession, CAS # | CAS: 118372-34-2 |
Catalog # | 21029-5 |
Price | $139.00 |
Order / More Info | SD-1029 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |