Naquotinib from CAYMAN CHEMICAL COMPANY
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| Product Name | Naquotinib |
| Description | An irreversible inhibitor of mutant EGFRs; inhibits cell proliferation of Ba/F3 cells expressing various EGFR mutations (IC50s= 9-11 nM); selective for mutant EGFRs over wild-type EGFR (IC50 = 830 nM); reduces phosphorylated levels of EGFR, AKT, and ERK and decreases cell viability in NSCLC cells and cells carrying an exon 20 insertion mutation; reduces tumor growth in PC-9/NaqRc2 mouse xenograft model at 50 mg/kg per day |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | F-3 T-790-M L-858-R C-797-S PC9 NaqRc-2 ASP8273 ASP-8273 |
| Gene, Accession, CAS # | CAS: 1448232-80-1 |
| Catalog # | 23498-5 |
| Price | $151.00 |
| Order / More Info | Naquotinib from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY