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Product Name | Naratriptan (hydrochloride) |
Description | A potent 5-HT1B and 5-HT1D receptor agonist (IC50s = 9.4 and 1.5 nM, respectively, in a radioligand binding assay using human recombinant receptors); selective for 5-HT1B and 5-HT1D, lacking activity in rat aorta, guinea pig colon, and pig vena cava that highly express 5-HT2A, 5-HT4, and 5-HT7 receptors, respectively, at concentrations up to 10 µM; induces contraction of isolated human coronary arteries (EC50 = 170 nM); induces dose-dependent vasoconstriction of the carotid vascular bed in dogs when administered at doses ranging from 1-300 µg/kg; inhibits plasma protein extravasation induced by electrical stimulation of the trigeminal ganglion in the dura of anesthetized rats, |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 121679-13-8 Amerge GR85548A Naramig Naratrex-1 5HT-2A 4 7 1D 1B GR-85548A 5HT2A 5HT4 5HT7 5HT1D 5HT1B |
Gene, Accession, CAS # | CAS: 143388-64-1 |
Catalog # | 23754-10 |
Price | $64.00 |
Order / More Info | Naratriptan (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |