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Product Name | KLH45 |
Description | An inhibitor of DDHD2 (IC50 = 1.3 nM); selective for DDHD2 over greater than 50 serine hydrolases, including DDHD1 and Sec23ip, but does inhibit ABHD6; inhibits DDHD2 and ABHD6 in Neuro2A cells at 95% at 25 nM; prevents increases in TAG hydrolase activity in HEK293T cell lysates expressing DDHD2 and incubated with a radiolabeled TAG substrate at 2 µM; decreases TAG levels in mouse CNS at 20 mg/kg twice per day for four days; reverses DDHD2-induced lipid droplet reduction in COS-7 cells expressing species recombinant DDHD2 and loaded with oleic acid at 2 µM |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | DDHD-2-1 serine hydrolase ABHD-6 TAG KLH-45 Sec-23ip HEK-293 Neuro-2A COS7 |
Gene, Accession, CAS # | CAS: 1632236-44-2 |
Catalog # | 19889-5 |
Price | $120.00 |
Order / More Info | KLH45 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |