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Product Name | JW 74 |
Description | An inhibitor of the catalytic PARP domain of TNKS1/2 that blocks canonical Wnt signaling with an IC50 value of 790 nM; decreases β-catenin levels in colorectal cancer (CRC) cells, leading to down-regulation of Wnt target genes; inhibits the growth of CRC xenograft tumors in mice |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1613543-73-9 JW74 tankyrase TNKS 1 TNKS 2 TNKS1 TNKS2 B-catenin Axin-2 |
Gene, Accession, CAS # | CAS: 863405-60-1 |
Catalog # | 19124-10 |
Price | $169.00 |
Order / More Info | JW 74 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |