JW 74 from CAYMAN CHEMICAL COMPANY

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Product NameJW 74
DescriptionAn inhibitor of the catalytic PARP domain of TNKS1/2 that blocks canonical Wnt signaling with an IC50 value of 790 nM; decreases β-catenin levels in colorectal cancer (CRC) cells, leading to down-regulation of Wnt target genes; inhibits the growth of CRC xenograft tumors in mice
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names1613543-73-9 JW74 tankyrase TNKS 1 TNKS 2 TNKS1 TNKS2 B-catenin Axin-2
Gene, Accession, CAS #CAS: 863405-60-1
Catalog #19124-10
Price$169.00
Order / More InfoJW 74 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com

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