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Product Name | KPT-6566 |
Description | A covalent PIN1 inhibitor ( IC50 = 0.64 µM); inhibits cell proliferation, decreases hyperphosphorylation of pRb, and reduces cyclin D1 levels in wild-type, but not Pin1-/-, MEFs; inhibits colony formation (IC50 = 1.2 µM) and impairs secondary mammosphere formation by MDA-MB-231 cells; reduces the number of lung metastases in an MDA-MB-231 mouse xenograft model at 5 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | KPT6566 PIN-1 MDAMB231 MDAMB |
Gene, Accession, CAS # | CAS: 881487-77-0 |
Catalog # | 37308-10 |
Price | $162.00 |
Order / More Info | KPT-6566 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |