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Product Name | Selonsertib |
Description | An ASK1 inhibitor (IC50 = 5.01 nM); decreases apoptosis and stellate cell activation in an in vitro 3D-human liver microtissue model of palmitic acid-induced NASH at 1 µM; sensitizes KB-C2 ABCB1-expressing epidermoid carcinoma cells to doxorubicin and paclitaxel; reduces hepatic necrosis and increases in serum TNF-α, IL-6, and CCL2 in a mouse model of LPS/D-galactosamine-induced acute liver failure at 15, 30, or 60 mg/kg |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | GS-4977|GS-4997 |
Gene, Accession, CAS # | CAS: 1448428-04-3 |
Catalog # | 20972-500 |
Price | $32.00 |
Order / More Info | Selonsertib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |