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Product Name | SGA360 |
Description | A selective modulator of AhR; competitively binds AhR (IC50 = 3 µM); represses IL-1β-induced SAA1 gene expression in Huh7 cells; reduces inflammation and decreases the mRNA expression of COX-2, IL-6, IL-1β, SAA3, and IL-10 in wild-type, but not AhR knockout, mice in a model of inflammatory ear edema; reduces acute inflammation in murine models of septic shock, gout, and peritonitis when the high-affinity AhR variant is expressed, |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SGA-360 IL1β Huh-7 COX2 IL6 IL10 SAA-1 3 IL1B KO interleukin cyclooxygenase |
Gene, Accession, CAS # | CAS: 680611-86-3 |
Catalog # | 21986-5 |
Price | $176.00 |
Order / More Info | SGA360 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |