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Product Name | Ipragliflozin |
Description | A SGLT2 inhibitor (IC50 = 7.4 nM in CHO cells expressing the human cotransporter); selective for SGLT2 over SGLT1, SGLT3, SGLT4, SGLT5, and SGLT6 (IC50s = 1.9, 30.4, 15.9, 0.46, and 10.4 µM, respectively); decreases plasma levels of insulin and glucose in an oral glucose tolerance test in a mouse model of diabetes induced by high-fat diet, STZ, and nicotinamide from 0.1-3 mg/kg; decreases plasma and hepatic IL-6, TNF-α, CCL2, and CRP levels in the same model at 3 mg/kg per day for 28 days |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ASP1941 |
Gene, Accession, CAS # | CAS: 761423-87-4 |
Catalog # | 22287-50 |
Price | $139.00 |
Order / More Info | Ipragliflozin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |