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Product Name | TM-N1324 |
Description | A GPR39 agonist; selective for GPR39 over a panel of 165 GPCRs, including GHS-R and the motilin receptor, at 1 µM; induces inositol phosphate accumulation in HEK293 cells expressing human GPR39 (EC50s = 2 and 201 nM in the presence and absence of zinc, respectively) and cAMP accumulation in COS-7 cells expressing human GPR39 (EC50 = 17 nM in the presence of zinc); decreases ghrelin secretion and increases somatostatin secretion in isolated mouse gastric mucosa cells at 1 µM; decreases food intake during the dark period and body weight in a mouse model of high-fat diet-induced obesity |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Compound 1324|Cpd1324 |
Gene, Accession, CAS # | CAS: 1144477-35-9 |
Catalog # | 37208-1 |
Price | $56.00 |
Order / More Info | TM-N1324 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |