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Product Name | TMS |
Description | CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids; eicosanoids) and exogenous xenobiotics such as polyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM.{10511} It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making it a useful tool to differentiate between various CYP450 families.{10511} In cultured human colon cancer cells, TMS induces apoptosis and inhibits cell growth with an IC50 of 0.8 µg/ml.{10510} |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2,3',4,5'-Tetramethoxystilbene |
Gene, Accession, CAS # | CAS: 24144-92-1 |
Catalog # | 10038-50 |
Price | $469.00 |
Order / More Info | TMS from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |