ZK 756326 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | ZK 756326 (hydrochloride) |
| Description | A non-peptide agonist of CCR8; inhibits binding of CCL1 to human CCR8 (IC50 = 1.8 µM); stimulates extracellular acidification in cells expressing human and mouse CCR8 (EC50s = 254 nM and 2.6 µM, respectively); exhibits >28-fold selectivity for CCR8 over 26 other GPCRs; binds to the serotonergic receptors 5-HT1A, 5-HT2B, 5-HT2C, and 5-HT5A (IC50s = 5.4, 4.4, 34.8, and 16 µM, respectively); induces Gαi-mediated calcium mobilization, ERK phosphorylation, exhibits leukocyte chemotactic activity, and inhibits HIV fusion of cells expressing CD4 and CCR8 |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 874911-96-3 ZK756326 CCR-8 CCL-1 U-87 5HT 1-A 2-B 2-C 5-A CD-4 |
| Gene, Accession, CAS # | CAS: 1780259-94-0 |
| Catalog # | 28454-5 |
| Price | $101.00 |
| Order / More Info | ZK 756326 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY