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Product Name | Tiopronin |
Description | An antioxidant with diverse biological activities; reduces free radical production by murine macrophages and granulocytes in vitro in a dose dependent manner; induces expression of HIF-1α and increases VEGF secretion in human colon carcinoma cells; rectal administration (500 µL of a 10 mM solution) reduces myeloperoxidase activity and reduces pro-inflammatory cytokine production in the colon in a rat model of colitis; reduces the incidence of cleft palate in fetuses born to female mice orally exposed to teratogenic methylmercury chloride; reduces heme oxygenase 1 mRNA expression, lipid peroxidation, and transverse aortic constriction in a mouse model of cardiac hypertrophy at a dose of 100 mg/kg; increases activity of superoxide dismutase and glutathione peroxidase and reverses hepatocyte degeneration in a rat model of high-fat diet-induced non-alcoholic steatohepatitis |
Size | 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | (±)-Tiopronin|BRN 1859822 |
Gene, Accession, CAS # | CAS: 1953-02-2 |
Catalog # | 23720-1 |
Price | $32.00 |
Order / More Info | Tiopronin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |