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Product Name | TMB 8 (hydrochloride) |
Description | A non-competitive antagonist of nAChRs (IC50s = 390 and 350 nM, respectively, for human muscle-type and and α3β4 subunit-containing ganglionic nAChRs); an inhibitor of intracellular calcium availability in smooth and skeletal muscle; blocks the contractile response in isolated rabbit aortic strip when used at a concentration of 50 µM; inhibits calcium influx and efflux in isolated guinea pig ileum when used at a concentration of 65 µM; used in the study of intracellular calcium dynamics; dose-dependently inhibits PKC activity |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 57818-92-5 TMB8 α3-β4 TE-671 SHSY5Y noncompetitive |
Gene, Accession, CAS # | CAS: 53464-72-5 |
Catalog # | 23928-10 |
Price | $50.00 |
Order / More Info | TMB 8 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |