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Product Name | RU-505 |
Description | An inhibitor of the Aβ and fibrinogen interaction; has a higher efficacy for the monomer form of Aβ bound to fibrinogen over the oligomer form; normalizes fibrin clot formation disrupted by the Aβ42-fibrinogen interaction (20 µM); decreases the incidence of vessel occlusion in Tg6799 mice, a model of Alzheimer's disease (35 mg/kg); decreases Aβ deposition in blood vessels and cortical fibrinogen infiltration and microgliosis in the brain of Tg6799 mice while improving spatial memory in chronically treated (35 mg/kg, s.c., every other day for 3 months) Tg6799 mice |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RU505 Tg-6799 Aβ-42 |
Gene, Accession, CAS # | CAS: 1314206-29-5 |
Catalog # | 16445-10 |
Price | $437.00 |
Order / More Info | RU-505 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |