GDC-0349 from CAYMAN CHEMICAL COMPANY
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| Product Name | GDC-0349 |
| Description | A potent inhibitor of mTOR (Ki = 3.8 nM); selective for mTOR over a panel of 266 kinases at a concentration of 1 µM; inhibits proliferation of PC3 prostate cancer cells in vitro (EC50 = 270 nM) and induces caspase-dependent apoptosis in HNSCC cells; oral administration inhibits tumor growth in MCF7-neo/Her-2 breast and PC3 prostate cancer mouse xenograft models in a dose-dependent manner (10-80 mg/kg) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GDC0349 PC-3 GDC349 349 Her2 MCF-7 |
| Gene, Accession, CAS # | CAS: 1207360-89-1 |
| Catalog # | 24058-5 |
| Price | $238.00 |
| Order / More Info | GDC-0349 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY