ITF 2357 from CAYMAN CHEMICAL COMPANY
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| Product Name | ITF 2357 |
| Description | Inhibits maize HDACs: HD2, HD-1B, and HD-1A (IC50s = 7.5-16 nM) and reduces TNFα, IL-1α, and IL-1β production (IC50s = 10-22 nM); inhibits activity of cells expressing JAK2V617F (IC50s = 1-10 nM), which are implicated in the pathophysiology of many myeloproliferative diseases |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 497833-27-9 givinostat histones deacetylases HDACs inhibitors inhibits inhibition pro-inflammatory cytokines janus kinases 2 JAK2 myeloproliferative diseases antitumor antiinflammatory anti-inflammatory anti inflammatory proinflammatory pro inflammatory HD2 HD-1B HD1A HD1B HD1A HD 1B HD 1A TNFα IL-1α IL-1β cytokines tumors necrosis factors interleukins cells JAK2V617F enzymes polycythaemia vera ITF-2357 ITF2357 |
| Gene, Accession, CAS # | CAS: 732302-99-7 |
| Catalog # | 11045-10 |
| Price | $220.00 |
| Order / More Info | ITF 2357 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY