IT-901 from CAYMAN CHEMICAL COMPANY
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| Product Name | IT-901 |
| Description | An inhibitor of the NF-κB subunit c-Rel; inhibits NF-κB DNA binding (IC50 = 0.1 µM); reduces TNF-α-induced NF-κB activity (IC50 = 4 µM); decreases proliferation of ABC and GCB DLBCLL cells at 3 µM; increases HO-1 expression and ROS production in mitochondria of DLBCL cells but not normal leukocytes; increases survival in a mouse model of GVHD at 24 mg/kg every other day beginning eight days after HSCT; reduces tumor growth in mouse xenograft models of EBV-induced B cell lymphoma, CLL, and Richter syndrome |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | IT901 NFκB cRel HBL-1 HO1 TNFα |
| Gene, Accession, CAS # | CAS: 1584121-99-2 |
| Catalog # | 22298-1 |
| Price | $32.00 |
| Order / More Info | IT-901 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY