GDC-0623 from CAYMAN CHEMICAL COMPANY
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| Product Name | GDC-0623 |
| Description | A potent, ATP-uncompetitive inhibitor of MEK1 (Ki = 0.13 nM in the presence of ATP); inhibits the proliferation of A375 BRAF(V600E) and HCT116 KRAS(G13D)-mutant cancer cell lines (EC50 = 7 and 42 nM, respectively); upregulates pro-apoptotic BIM |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1443238-25-2 MEK1 MEK-1 MAP GDC0623 ATP-uncompetitive A375 BRAF V600E HCT116 KRAS G13D ERK BIM phosphorylation GW620 |
| Gene, Accession, CAS # | CAS: 1168091-68-6 |
| Catalog # | 19479-10 |
| Price | $201.00 |
| Order / More Info | GDC-0623 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY