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Product Name | Astragaloside II |
Description | A triterpene saponin with diverse biological activities; increases the phosphatase activity of CD45 in cell-free assays using pNPP or OMFP as substrates (EC50s = 9.23 and 5.37 µg/ml, respectively); inhibits replication of dengue virus serotypes 1 and 3 in infected Vero cells (MIC = 1.56 µg/ml for both); increases concanavalin A-induced proliferation of primary mouse splenocytes at 30 nM; inhibits autophagy and enhances apoptosis induced by cisplatin in SGC-7901 gastric cancer cells at 50 µM; prevents decreases in small intestine and colon length, as well as body weight, in a mouse model of TNBS-induced colitis at 10 mg/kg; decreases the urinary albumin-to-creatinine ratio and improves histopathological scores in a rat model of STZ-induced diabetic nephropathy at 3.2 and 6.4 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Astrasieversianin VIII|NSC 641295 |
Gene, Accession, CAS # | CAS: 84676-89-1 |
Catalog # | 40139-10 |
Price | $207.00 |
Order / More Info | Astragaloside II from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |