NVP-CGM097 from CAYMAN CHEMICAL COMPANY
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| Product Name | NVP-CGM097 |
| Description | An inhibitor of the MDM2-p53 interaction (IC50 = 1.7 nM for human MDM2 in a TR-FRET assay); selective for human MDM2 (Ki = 1.3 nM) over dog, mouse, and rat Mdm2 (Kis = 20.5, 65.9, and 47.4 nM, respectively); selectively inhibits proliferation of AML cells expressing wild-type p53 (IC50s = 50-1,000 nM) over AML cells expressing mutant p53 (IC50s = >1,000 nM); induces tumor regression in a PDX mouse model of AML at 100 mg/kg per day |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CGM-097 NVPCGM097 NVP-CGM NVPCGM-097 MDM2p53 p-53 MDM-2 TRFRET |
| Gene, Accession, CAS # | CAS: 1313363-54-0 |
| Catalog # | 29519-1 |
| Price | $93.00 |
| Order / More Info | NVP-CGM097 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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