Edit |   |
---|---|
Product Name | IQ-1S (free acid) |
Description | An inhibitor of NF-κB/AP-1 (IC50 = 2.3 µM in a reporter assay); inhibits the production of TNF-α and IL-6 production in human Mono-Mac-6 cells (IC50s = 1.3 and 3.8 µM, respectively) and isolated human PBMCs (IC50s = 2.6 and 5.6 µM, respectively), as well as NO production in murine J774-A.1 macrophages (IC50 = 3.1 µM); binds to JNKs (Kd = 0.24, 0.36, and 0.1 for JNK1-3), as well as CK1δ, PI3Kγ, and MKNK2 (Kds = 0.38, 0.47, and 0.92 µM, respectively) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | IQ-1 |
Gene, Accession, CAS # | CAS: 23146-22-7 |
Catalog # | 29851-10 |
Price | $145.00 |
Order / More Info | IQ-1S (free acid) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |