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Product Name | 5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine |
Description | An mPGES-1 inhibitor (IC50s = 66 and 2,730 nM for human and mouse enzymes, respectively); selective for mPGES-1 over COX-1 but does inhibit COX-2 at 20 µM; inhibits LPS-induced PGE2 production in mouse peritoneal cells (IC50 = 12 nM); reduces carrageenan-induced paw edema in rats at 25 mg/kg |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | mPGES1 COX1 COX2 PGE 2 |
Gene, Accession, CAS # | CAS: 2253745-78-5 |
Catalog # | 31338-500 |
Price | $84.00 |
Order / More Info | 5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |