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Product Name | NFAT Inhibitor |
Description | A peptide inhibitor of NFAT; binds to the NFAT recognition site on calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity at 100 µM; inhibits the dephosphorylation of NFAT in HEK293T lysates expressing NFAT1, -2, or -4; inhibits NFAT activation in RAW 264.7 macrophages, EA.hy926 endothelial cells, and isolated mouse thoracic aorta VSMCs (IC50s = 29.1, 30.2, and 45.7 µM, respectively, in reporter assays) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ?Nuclear Factor of Activated T cells Inhibitor|VIVIT |
Gene, Accession, CAS # | CAS: 249537-73-3 |
Catalog # | 13855-1 |
Price | $82.00 |
Order / More Info | NFAT Inhibitor from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |