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Product Name | GNE-493 |
Description | A dual inhibitor of PI3K and mTOR (IC50s = 3.4, 12, 16, and 16 nM for PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively); inhibits proliferation of PC3 and MCF-7.1 cells (IC50s = 330 and 180 nM, respectively); reduces tumor volume in PC3 and MCF-7.1 mouse xenograft models at 10 mg/kg per day |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | GNE493 PI-3K PI3-K m-TOR α β δ γ PC-3 MCF7.1 PRAS-40 S-6RP S6-RP |
Gene, Accession, CAS # | CAS: 1033735-94-2 |
Catalog # | 29224-25 |
Price | $1,201.00 |
Order / More Info | GNE-493 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |