DuP-697 from CAYMAN CHEMICAL COMPANY
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| Product Name | DuP-697 |
| Description | DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2.{4313} When tested on isolated recombinant enzymes, DuP-697 is at least 50 times more potent in the inhibition of COX-2 than COX-1.{7452} The IC50 values for human recombinant COX-2 are 80 and 40 nM at 5 and 10 minutes, respectively.{8512} The IC50 for the inhibition of human recombinant COX-1 after the same time intervals is 9 µM.{8512} DuP-697 also attenuates the COX-1 inhibitory activity of non-selective COX inhibitors such as indomethacin.{8048} |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | COX-2 COX2 PGHS2 prostaglandins H synthases inhibitors inhibits selective time-dependent cyclooxygenase DuP697 |
| Gene, Accession, CAS # | CAS: 88149-94-4 |
| Catalog # | 70645-50 |
| Price | $757.00 |
| Order / More Info | DuP-697 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
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