XL647 from CAYMAN CHEMICAL COMPANY
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| Product Name | XL647 |
| Description | A multi-kinase inhibitor (IC50s = 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, FLT4, and EphB4, respectively); selective for these kinases over a panel of 10 tyrosine kinases and 55 serine/threonine kinases at 10 µM; inhibits growth of A431 cells expressing wild-type EGFR and H1975 NSCLC cells expressing both EGFRL858R and EGFRT790M (IC50s = 13 and 920 nM, respectively); inhibits tumor growth and EGFR phosphorylation in an H1975 mouse xenograft model at 10, 30, and 100 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | EXEL-7647|Tesevatinib |
| Gene, Accession, CAS # | CAS: 781613-23-8 |
| Catalog # | 27049-1 |
| Price | $97.00 |
| Order / More Info | XL647 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY