GS-444217 from CAYMAN CHEMICAL COMPANY
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| Product Name | GS-444217 |
| Description | An AKS1 inhibitor (IC50 = 2.87 nM); selective for ASK1 over 442 additional kinases at 1 µM; inhibits phosphorylation of the ASK1 substrates MKK3, MKK6, and MKK4, as well as p38 MAPK and JNK in HEK293T cells expressing human ASK1 from 0.001-10 µM; reduces renal fibrosis and proteinuria in a db/db eNOS-/- mouse model of DKD at 0.3% w/w |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Apoptosis Signal-regulating Kinase 1 Inhibitor 1|Apoptosis Signal-regulating Kinase 1-IN-1|ASK1 Inhibitor 1|ASK1-IN-1 |
| Gene, Accession, CAS # | CAS: 1262041-49-5 |
| Catalog # | 40757-25 |
| Price | $237.00 |
| Order / More Info | GS-444217 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY