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Product Name | Kobe 0065 |
Description | An orally active Ras inhibitor with selectivity for H-Ras (Ki = 46 µM); inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 = ~1.5 µM); exhibits antitumor activity in mice bearing a xenograft of human colon cancer SW480 cells expressing K-RasG12V at an oral dose of 80 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Kobe0065 Ras inhibitor H-Ras apoptosis antitumor cancer biochemical intracellular signaling signal transduction |
Gene, Accession, CAS # | CAS: 436133-68-5 |
Catalog # | 16261-1 |
Price | $37.00 |
Order / More Info | Kobe 0065 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |