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Product Name | SGC-SMARCA-BRDVIII |
Description | A pan-family VIII BRD inhibitor; selectively binds to PBRM1 bromodomain 5, BRM, and BRG1 over PBRM1 bromodomain 2, PBRM1 bromodomain 3, and PBRM1 bromodomain 4 (Kds = 13, 35, 36, 3,655, 1,963, and >10,000 nM, respectively); decreases rosiglitazone-induced lipid accumulation in 3T3-L1 mouse fibroblasts differentiated into adipocytes by IBMX, dexamethasone, and insulin; decreases expression of the genes encoding PPARγ, C/EBPα, and FABP4 in the same cells at 0.5 µM |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SGCSMARCABRDVIII SGCSMARCA-BRDVIII SGC-SMARCABRDVIII PBRM-1 SMARCA-2 4 BRG-1 3T3L1 FABP-4 structural genomics consortium |
Gene, Accession, CAS # | CAS: 1997319-84-2 |
Catalog # | 33567-25 |
Price | $320.00 |
Order / More Info | SGC-SMARCA-BRDVIII from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |