COG133 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
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| Product Name | COG133 (trifluoroacetate salt) |
| Description | A peptide fragment of ApoE and an α7 nAChR antagonist (IC50 = 720 nM); suppresses TNF-α and NO release in BV-2 microglia from 10-50 µM; reduces LPS-induced increases in brain levels of TNF-α and IL-6 in mice; decreases hippocampal neuronal degeneration and the latency to find the platform in the Morris water maze in a mouse model of closed head injury induced by surgical midline impact at 203 and 406 µg/kg; delays disease onset and reduces disease severity in a mouse model of EAE at 1 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Ac-LRVRLASHLRKLRKRLL-NH2|ApoE (133-149) |
| Gene, Accession, CAS # | CAS: 514200-66-9 |
| Catalog # | 33587-5 |
| Price | $410.00 |
| Order / More Info | COG133 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY