GN44028 from CAYMAN CHEMICAL COMPANY
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| Product Name | GN44028 |
| Description | An inhibitor of HIF-1α transcriptional activity; reduces HIF-1α reporter gene expression in HeLa cells (IC50 = 14 nM); induces cytotoxicity in HCT116, HepG2, PC3, and HeLa cells (IC50s = 2.1, 3.7, 25.4, and 2.1 µM, respectively); reduces the levels of VEGF, but not HIF-1α or HIF-1α-HIF-1β dimer levels, in HeLa cells at 0.1 and 1 µM; decreases tumor volume and the number of lung metastases and increases survival percentage alone or in combination with 5-fluorouracil in a CT26 murine colon cancer model at 5 mg/kg twice per week |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GN-44028 HIF1α HCT-116 Hep-G2 PC-3 HIF1β CT-26 |
| Gene, Accession, CAS # | CAS: 1421448-26-1 |
| Catalog # | 37289-5 |
| Price | $126.00 |
| Order / More Info | GN44028 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com
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