BDKRB2 from CREATIVE BIOLABS, INC.
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| Product Name | BDKRB2 |
| Description | Magic™ Membrane Protein Human BDKRB2 (Bradykinin receptor B2). The B2R is a receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. The B2 receptor mediates slow contraction of various smooth muscles including veins, intestine, uterus, trachea and lung, inducing endothelium-dependent relaxation of arteries and arterioles, and stimulates natriuresis/diuresis in kidney. The B2 receptor couples to Gq and Gi, Gq stimulates phospholipase C to increase intracellular free calcium and Gi inhibits adenylate cyclase. Furthermore, the receptor stimulates the mitogen-activated protein kinase pathways. The B2 receptor also forms a complex with angiotensin converting enzyme (ACE) and this is thought to play a role in cross-talk between the renin-angiotensin system (RAS) and the kinin-kallikrein system (KKS). Histidine tag fused to the N-terminal end of the protein. Purity >75% by SDS-Page and Coomassie Blue staining |
| Size | n/a |
| Concentration | n/a |
| Applications | Screening & display technologies, Structural biology, Antibody development. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. |
| Other Names | B2R, BK2, BK-2, BKR2, BRB2 |
| Gene, Accession, CAS # | Gene ID: 624, UniProt: P30411 |
| Catalog # | MP0003F |
| Price | please inquire |
| Order / More Info | BDKRB2 from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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