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Product Name | Human Recombinant Transthyretin Y78F Variant Protein Filaments, 100 µg |
Description | Transthyretin is a transport protein in the serum and cerebospinal fluid that carried the thyroid hormone Thyroxine and retinol-binding protein bound to retinol. TTR misfolding and aggregation is known to be associated with the amyloiddiseases SSA, FAP and FAC (1-5). TTR is also thought to have beneficial side effects, such as binding to beta-amyloid protein, preventing beta-amyloid from accumulating into the plaques associated with Alzheimer's Disease (6). The mutant variant Y78F indicates a destabilization of the contacts between the alpha-helix and AB loop and the body of the molecule, potentially leading to applications in immne therapy for FAP (7). |
Size | 100 µg |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | SPR-465B |
Price | $560 |
Order / More Info | Human Recombinant Transthyretin Y78F Variant Protein Filaments, 100 µg from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |