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Product Name | iLite ADCC Target EGFR (+) Assay Ready Cells |
Description | Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism whereby pathogenic cells are lysed by lymphocytes, most often Natural Killer (NK) cells. The mechanism involves binding of antibodies to surface antigens on the pathogen. Crosslinking of these antibodies to NK cells through the binding of the Fc-portion to Fc receptors on the NK cells leads to activation of the NK cell and formation of an immune synapse with the pathogenic cell. The NK cell releases cytotoxic granules containing granzymes and perforin into the synapse, leading to apoptosis of the targeted cell (1). |
Size | 250 ul |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | BM5035 |
Price | $1060 |
Order / More Info | iLite ADCC Target EGFR (+) Assay Ready Cells from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |