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Product Name | Human [Ala31] IGF-I |
Description | Human [Ala31]insulin-like Growth Factor-I ([Ala31]IGF-I) is an analogue of human IGF-I which has an Alanine substitution in place of Tyrosine at position 31 of the human IGF-I sequence. [Ala31]IGF-I has normal binding to acid-stripped human serum binding proteins but has reduced binding to the type 1 IGF receptor and to the insulin receptor compared to IGF-I. It has a slightly higher affinity for the type 1 IGF receptor than [Leu24]IGF-I and [Leu60]IGF-I and is able to elicit a weak biological response through this receptor. It is a useful analogue for studying the balance of effects of IGF-I through the type 1 receptor and IGF binding proteins. |
Size | 100 µg |
Concentration | n/a |
Applications | RUO |
Other Names | IGF-II |
Gene, Accession, CAS # | n/a |
Catalog # | AIU100 |
Price | $180 |
Order / More Info | Human [Ala31] IGF-I from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |