Tau-352 (fetal 0N3R) Pre-formed Fibrils from EAGLE BIOSCIENCES INC.
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| Product Name | Tau-352 (fetal 0N3R) Pre-formed Fibrils |
| Description | Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65. Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrallary tangles containing paired helical filaments (PHFs). Brain-specific tau isoforms vary in the number of N-terminal inserts and C-terminal repeat domains due to alternative splicing of exons; only the shortest isoform of tau, 0N3R, is expressed in the fetal brain during neurogenesis. Three-repeat (3R) isoforms have been shown tobe more prone than four-repeated (4R) isoforms to form oligomers in vitro. The Beta-sheet core of Tau 0N3R fibrilized using heparin differs from all other tau fibril structures known to date. |
| Size | 100 ug |
| Concentration | n/a |
| Applications | RUO |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | SPR-491B |
| Price | $645 |
| Order / More Info | Tau-352 (fetal 0N3R) Pre-formed Fibrils from EAGLE BIOSCIENCES INC. |
| Product Specific References | n/a |
EAGLE BIOSCIENCES INC.
EAGLE BIOSCIENCES INC.
20A NW Blvd., Suite 112
Nashua NH 03063
P: 617-419-2019
P: 866-411-8023
F: 617-419-1110
info@EagleBio.com
http://www.EagleBio.com
Profile of EAGLE BIOSCIENCES INC.