Edit |   |
---|---|
Product Name | Oxidized PAPC |
Description | Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (OxPAPC) is a prototypic biologically active oxidized phospholipid first isolated from LDL minimally modified by oxidation (MM-LDL). OxPAPC is an active principle of MM-LDL that mimics several pro- and anti-inflammatory effects induced by oxidized lipoproteins. Oxidation of PAPC generates a mixture of oxidized phospholipids containing either fragmented or full-length oxygenated sn-2 residues. The best-characterized oxidatively fragmented species contain a five-carbon sn-2 residue bearing omega-aldehyde or omega-carboxyl groups. Oxydation of arachidonic acid residue also produces phospholipids containing esterified isoprostanes. Both fragmented and full-length oxygenated species can regulate immune reactions. Pro-inflammatory effects of OxPAPC include stimulation of endothelial cells to bind monocytes and induction of tissue clotting factor, IL-8, MCP-1, G-CSF and other mediators of atherothrombosis. Anti-inflammatory effec |
Size | 5 mg |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | HC4036-5mG |
Price | $1295 |
Order / More Info | Oxidized PAPC from HYCULT BIOTECH |
Product Specific References | n/a |