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Product Name | MutaCHIP® CYP+ (P450 2D6, 1A1, 1A2, 2B6, 2C9, 2C19, 3A4, 3A5 and VKORC1 ) |
Description | The CYP + test kit is a biomolecular test for the analysis of mutations and polymorphisms in the Cytochrome P450 2D6, 1A1, 1A2, 2B6, 2C9, 2C19, 3A4, 3A5 and VKORC1 genes from genomic DNA. The test is based on the macroarray technology. The investigated genetic variants are associated with decreased, increased or no activity of the respective enzymes. The target gene sequences are amplified by PCR. After a denaturation step, the amplification products are transferred to the Array Tube. Here the amplified products bind to the complementary probes immobilized on the Array. A washing step removes unspecifically bound fragments. In the next step the Conjugation Mix is added and binds to the probe-PCR-fragment complexes. Another washing step removes the unbound Conjugation Mix residues. Subsequent addition of the substrate results in a precipitation reaction only at those spots where the target gene sequence has previously bound. The overall precipitation pattern is detected by the image reader and interpreted by the corresponding software. |
Size | 20 Chips |
Concentration | n/a |
Applications | n/a |
Other Names | CYP+ |
Gene, Accession, CAS # | n/a |
Catalog # | KF390014 |
Price | please inquire |
Order / More Info | MutaCHIP® CYP+ (P450 2D6, 1A1, 1A2, 2B6, 2C9, 2C19, 3A4, 3A5 and VKORC1 ) from IMMUNDIAGNOSTIK AG |
Product Specific References | n/a |