Canine Osteosarcoma Cell Line (OSCA-40) from KERAFAST, INC.

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Product NameCanine Osteosarcoma Cell Line (OSCA-40)
DescriptionSource: Bone (femur). Cell type: Osteosarcoma.
Size1 vial
Concentrationn/a
Applicationsn/a
Other Namesn/a
Gene, Accession, CAS #Accession: CVCL_L389
Catalog #EMN003-FP
Price$605
Order / More InfoCanine Osteosarcoma Cell Line (OSCA-40) from KERAFAST, INC.
Product Specific References
  1. Wolfe TD, Pillai SP, Hildreth BE 3rd, Lanigan LG, Martin CK, Werbeck JL, Rosol TJ. Effect of zoledronic acid and amputation on bone invasion and lung metastasis of canine osteosarcoma in nude mice. Clin Exp Metastasis. 2011 Apr;28(4):377-89. doi: 10.1007/s10585-011-9377-9. Epub 2011 Mar 4.
  2. Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF. Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach. Bone. 2011 Sep;49(3):356-67. doi: 10.1016/j.bone.2011.05.008. Epub 2011 May 15.
  3. Wells JW, Evans CH, Scott MC, Rutgen BC, O'Brien TD, Modiano JF, Cvetkovic G, Tepic S. Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation. PLoS One. 2013;8(1):e54464. doi: 10.1371/journal.pone.0054464. Epub 2013 Jan 24.
  4. Cannon CM, Pozniak J, Scott MC, Ito D, Gorden BH, Graef AJ, Modiano JF. Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors. Vet Comp Oncol. 2015 Mar;13(1):48-59. doi: 10.1111/vco.12018. Epub 2013 Feb 15.
  5. Murahari S, Jalkanen AL, Kulp SK, Chen CS, Modiano JF, London CA, KisseberthWC. Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis.BMC Cancer. 2017 Jan 21;17(1):67. doi: 10.1186/s12885-017-3046-6. PubMed PMID:28109246; PubMed Central PMCID: PMC5251323.
  6. Scott MC, Tomiyasu H, Garbe JR, Cornax I, Amaya C, O'Sullivan MG, Subramanian S, Bryan BA, Modiano JF. Heterotypic mouse models of canine osteosarcomarecapitulate tumor heterogeneity and biological behavior. Dis Model Mech. 2016Dec 1;9(12):1435-1444. Epub 2016 Nov 3. PubMed PMID: 27874835; PubMed CentralPMCID: PMC5200896.
  7. Fenger JM, Roberts RD, Iwenofu OH, Bear MD, Zhang X, Couto JI, Modiano JF,Kisseberth WC, London CA. MiR-9 is overexpressed in spontaneous canineosteosarcoma and promotes a metastatic phenotype including invasion and migrationin osteoblasts and osteosarcoma cell lines. BMC Cancer. 2016 Oct 10;16(1):784.PubMed PMID: 27724924; PubMed Central PMCID: PMC5057229.
  8. Scott MC, Sarver AL, Tomiyasu H, Cornax I, Van Etten J, Varshney J, O'SullivanMG, Subramanian S, Modiano JF. Aberrant Retinoblastoma (RB)-E2F TranscriptionalRegulation Defines Molecular Phenotypes of Osteosarcoma. J Biol Chem. 2015 Nov20;290(47):28070-83. doi: 10.1074/jbc.M115.679696. Epub 2015 Sep 16. PubMed PMID:26378234; PubMed Central PMCID: PMC4653667.
  9. Im KS, Graef AJ, Breen M, Lindblad-Toh K, Modiano JF, Kim JH. Interactionsbetween CXCR4 and CXCL12 promote cell migration and invasion of caninehemangiosarcoma. Vet Comp Oncol. 2017 Jun;15(2):315-327. doi: 10.1111/vco.12165. Epub 2015 Sep 3. PubMed PMID: 26337509.
  10. Lin W, Modiano JF, Ito D. Stage-specific embryonic antigen: determiningexpression in canine glioblastoma, melanoma, and mammary cancer cells. J Vet Sci.2017 Mar 30;18(1):101-104. doi: 10.4142/jvs.2017.18.1.101. PubMed PMID: 27456773;PubMed Central PMCID: PMC5366293.
  11. Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL. Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma. Cancer Res. 2017 Oct 24. pii: canres.0576.2017. View Article
KERAFAST, INC.
KERAFAST, INC.
KERAFAST, INC.
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