CD41/CD61 Antibody Kit, anti-human, PE, REAlease® from MILTENYI BIOTEC B.V. & Co. KG
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| Product Name | CD41/CD61 Antibody Kit, anti-human, PE, REAlease® |
| Description | CD41/CD61 Antibody Kit, anti-human, PE, REAlease®. Clone REAL179 is an antibody fragment derived from the full CD41/CD61 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL179 recognizes the CD41/CD61 complex, also known as gpIIb/IIIa complex or integrin αIIbβ3. This cell adhesion molecule is an α/β transmembrane heterodimer of the ubiquitous integrin superfamily which is expressed by megakaryocytes and platelets. The CD41/CD61 complex plays an significant role in hemostasis and is also involved in fibrinogen binding and platelet aggregation. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |
| Size | 100 tests |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Other Names | gpIIb/IIIa complex, integrin αIIbβ3 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 130-122-682 |
| Price | $425 |
| Order / More Info | CD41/CD61 Antibody Kit, anti-human, PE, REAlease® from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Naik, U. P. et al. (1997) Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain. J. Biol. Chem. 272 (8): 4651-4654. | Corbel, C. et al. (2005) (alpha)IIb integrin, a novel marker for hemopoietic progenitor cells. Int. J. Dev. Biol. 49 (2-3): 279-284. | Podolnikova, N. P. et al. (2014) The interaction of integrin αIIbβ3 with fibrin occurs through multiple binding sites in the αIIb β-propeller domain. J. Biol. Chem. 289 (4): 2371-2383. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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