CD200R3 Antibody Kit, anti-mouse, APC, REAlease® from MILTENYI BIOTEC B.V. & Co. KG
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| Product Name | CD200R3 Antibody Kit, anti-mouse, APC, REAlease® |
| Description | CD200R3 Antibody Kit, anti-mouse, APC, REAlease®. Clone REAL249 is an antibody fragment derived from the full CD200R3 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL249 recognizes the human CD200R3 antigen. CD200R is an approximately 33 kDa single-pass type I membrane-protein which is a disulfide-linked dimer on the cell surface. It is reported, that the four different isoforms of CD200R (CD200R1, CD200R2, CD200R3, CD200R4) bind to CD200 (OX-2) as ligand. CD200 is primarily expressed on myeloid cells but also expressed on T and B lymphocytes. The combination of CD200R and CD200 inhibits mast cell degranulation, promotes macrophage activation, and decreases the activation of lymphocytes. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |
| Size | 100 tests |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Other Names | OX-2 receptor 3 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 130-122-653 |
| Price | $162 |
| Order / More Info | CD200R3 Antibody Kit, anti-mouse, APC, REAlease® from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wright, G. J. et al. (2003) Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol 171: 3034-3046. | Gorczynski, R. et al. (2004) CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules. J Immunol 172: 7744-7749. | Rijkers, E. S. et al. (2008) The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes. Mol. Immunol. 45 (4): 1126-1135. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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